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Literature summary for 3.6.5.1 extracted from

  • Choudhury, S.R.; Westfall, C.S.; Laborde, J.P.; Bisht, N.C.; Jez, J.M.; Pandey, S.
    Two chimeric regulators of G-protein signaling (RGS) proteins differentially modulate soybean heterotrimeric G-protein cycle (2012), J. Biol. Chem., 287, 17870-17881.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.5.1

Activating Compound

Activating Compound Comment Organism Structure
RGS1 protein G-protein signaling proteins, RGS proteins, accelerate the inherent GTPase activity of Galpha proteins. The GTPase-accelerating activities of GmRGS1 and -2 differ for each GmGalpha. Differential effects of GmRGS1 and GmRGS2 on GmGalpha1-4 result from a single valine versus alanine difference. GmRGS protein sequence comparisons and expression pattern, overview Glycine max
RGS2 protein G-protein signaling proteins, RGS proteins, accelerate the inherent GTPase activity of Galpha proteins. The GTPase-accelerating activities of GmRGS1 and -2 differ for each GmGalpha. Differential effects of GmRGS1 and GmRGS2 on GmGalpha1-4 result from a single valine versus alanine difference. GmRGS protein sequence comparisons and expression pattern, overview Glycine max

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics of 2'-/3'-O-N'-methylanthraniloyl-labeled GTP/GDP exchange for GmGalpha1-GmGalpha4, overview. GmGalpha1 and GmGalpha4 bind GTP more rapidly thanGmGalpha2 and GmGalpha3 Glycine max

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Glycine max

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Glycine max
-
 GDP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Glycine max
-
 cv. Jack Seeds, four soybean Galpha proteins GmGalpha1-4
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information expression patterns of GmGalpha1-4 are differentially regulated in different tissues of soybean and at various growth and development phases, e.g. during seed development and seed germination Glycine max
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
 Glycine max GDP + phosphate
-
 ?

Subunits

Subunits Comment Organism
heterotrimer
-
 Glycine max

Synonyms

Synonyms Comment Organism
heterotrimeric G-protein
-
 Glycine max

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
20 25 assay at Glycine max

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Glycine max

General Information

General Information Comment Organism
metabolism complex regulation of the G-protein cycle in soybean and in other plants with expanded G-protein networks Glycine max
physiological function Galpha proteins regulate G-protein signaling working with RGS proteins Glycine max