Literature summary for 3.6.5.1 extracted from

Dave, R.H.; Saengsawang, W.; Yu, J.Z.; Donati, R.; Rasenick, M.M.
Heterotrimeric G-proteins interact directly with cytoskeletal components to modify microtubule-dependent cellular processes (2009), Neurosignals, 17, 100-108.

Search for more literature for 3.6.5.1

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	tubulin binds to G beta1gamma1, promotes microtubule stability	Homo sapiens
additional information	tubulin binds to Gs alpha	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	tubulin binds to Gs alpha, Gi alpha1 and Gq alpha, destabilize microtubules	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Homo sapiens	5829	-
membrane	lipid rafts	Mus musculus	16020	-
membrane	lipid rafts	Homo sapiens	16020	-
membrane	lipid rafts	Rattus norvegicus	16020	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Mus musculus	-	-	-
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-
brain	synaptic membrane	Rattus norvegicus	-
HeLa cell	-	Homo sapiens	-
monocyte	-	Homo sapiens	-
neuron	neonatal neuron	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
G betagamma	-	Homo sapiens
Gs alpha	-	Rattus norvegicus
heterotrimeric G-protein	-	Mus musculus
heterotrimeric G-protein	-	Homo sapiens
heterotrimeric G-protein	-	Rattus norvegicus

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Release 2023.1 (January 2023)