Literature summary for 3.6.5.1 extracted from

Brito, M.; Guzman, L.; Romo, X.; Soto, X.; Hinrichs, M.V.; Olate, J.
S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate (2002), J. Cell. Biochem., 85, 615-620.

Protein Variants

Protein Variants	Comment	Organism
S111N	mutation at carboxy-terminal end of helix alpha of helical domain, decreased nucleotide exchange kinetics, impaired adenylyl cyclase activation with GTPgammaS, but normal receptor and AlF4- activation	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)