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Literature summary for 3.6.4.B8 extracted from
- On the mechanism of loading the PCNA sliding clamp by RFC (2008), Mol. Microbiol., 68, 216-222.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharolobus solfataricus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | model of the clamp loading process: ATP-bound replication factor C forms a complex with replication factor C. This results in in-plane opening of a single interface of Proliferating-Cell-Nuclear-Antigen (PCNA) and allowing entry of DNA | Saccharolobus solfataricus | ADP + phosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| clamp loader complex | - |
Saccharolobus solfataricus |
| RFC | - |
Saccharolobus solfataricus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | sliding clamps play central roles in a broad range of DNA replication and repair processes. The clamps form circular molecules that must be opened and resealed around DNA by the clamp loader complex to fulfil their function | Saccharolobus solfataricus |
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Release 2023.1 (January 2023)
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