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Literature summary for 3.6.4.B1 extracted from
- Kinesin superfamily protein member 4 (KIF4) is localized to midzone and midbody in dividing cells (2004), Exp. Mol. Med., 36, 93-97.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chromosome | in addition to association with segregating chromosomes through entire mitosis, it also localizes to the midzone and to midbody at ana/telophase through cytokinesis. In cells at cytokinesis, KIF4 appears as a doublet facing each other at the apical ends of two daughter cells | Homo sapiens | 5694 | - |
| microtubule | KIP4 forms a ring structure wrapping around the microtubule bundles | Homo sapiens | 5874 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | Homo sapiens | KIF4 is involved in cytokinesis | ADP + phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HeLa cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | - |
Homo sapiens | ADP + phosphate | - |
? | |
| ATP + H2O | KIF4 is involved in cytokinesis | Homo sapiens | ADP + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| KIF4 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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