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Literature summary for 3.6.4.7 extracted from

  • Tsukamoto, T.; Miura, S.; Nakai, T.; Yokota, S.; Shimozawa, N.; Suzuki, Y.; Orii, T.; Fujiki, Y.; Sakai, F.; Bogaki, A.
    Peroxisome assembly factor-2, a putative ATPase cloned by functional complementation on a peroxisome-deficient mammalian cell mutant (1995), Nature Genet., 11, 395-401.
    View publication on PubMed

Application

Application Comment Organism
medicine
-
Cricetulus griseus
medicine
-
Rattus norvegicus
medicine diagnosis of inherited peroxisome-deficient diseases such as Zellweger syndrome by functional complementation Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
PCR-based cDNA cloning of human PAF-2 to identify mutations in the PAF-2 gene of patients using a mammalian expression vector is under way Homo sapiens
peroxisome assembly factor-2 cloned from rat cDNA Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
PAF-1 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Cricetulus griseus
-
ADP + phosphate
-
?
ATP + H2O Homo sapiens
-
ADP + phosphate
-
?
ATP + H2O Rattus norvegicus
-
ADP + phosphate
-
?
ATP + H2O Saccharomyces cerevisiae
-
ADP + phosphate
-
?
ATP + H2O Komagataella pastoris
-
ADP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Cricetulus griseus
-
chinese hamster
-
Homo sapiens
-
human
-
Komagataella pastoris
-
-
-
Rattus norvegicus
-
rat
-
Saccharomyces cerevisiae
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O = ADP + phosphate an extremely diversified group of enzymes that use the energy of ATP hydrolysis to import and assemble peroxisome components into the organelle. Their molecular masses range from 25 to 600 kDa Cricetulus griseus
ATP + H2O = ADP + phosphate an extremely diversified group of enzymes that use the energy of ATP hydrolysis to import and assemble peroxisome components into the organelle. Their molecular masses range from 25 to 600 kDa Homo sapiens
ATP + H2O = ADP + phosphate an extremely diversified group of enzymes that use the energy of ATP hydrolysis to import and assemble peroxisome components into the organelle. Their molecular masses range from 25 to 600 kDa Rattus norvegicus
ATP + H2O = ADP + phosphate an extremely diversified group of enzymes that use the energy of ATP hydrolysis to import and assemble peroxisome components into the organelle. Their molecular masses range from 25 to 600 kDa Saccharomyces cerevisiae
ATP + H2O = ADP + phosphate an extremely diversified group of enzymes that use the energy of ATP hydrolysis to import and assemble peroxisome components into the organelle. Their molecular masses range from 25 to 600 kDa Komagataella pastoris

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
-
fibroblast
-
Homo sapiens
-
liver
-
Homo sapiens
-
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
Cricetulus griseus ADP + phosphate
-
?
ATP + H2O
-
Homo sapiens ADP + phosphate
-
?
ATP + H2O
-
Rattus norvegicus ADP + phosphate
-
?
ATP + H2O
-
Saccharomyces cerevisiae ADP + phosphate
-
?
ATP + H2O
-
Komagataella pastoris ADP + phosphate
-
?

Synonyms

Synonyms Comment Organism
PAS1
-
Saccharomyces cerevisiae
PAS1
-
Komagataella pastoris
PAS8
-
Komagataella pastoris