Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
140000 | - |
MALDI-TOF | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | RNA helicase A interacts with La ribonucleoprotein domain family member 6 (LARP6) which recruits RHA to the 5' UTR of collagen mRNAs | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | RNA helicase A interacts with La ribonucleoprotein domain family member 6 (LARP6) which recruits RHA to the 5' UTR of collagen mRNAs | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
RHA | - |
Homo sapiens |
RNA helicase A | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | knockdown of RHA prevents formation of polysomes on collagen mRNAs and dramatically reduces synthesis of collagen protein, without affecting the level of the mRNAs | Homo sapiens |
physiological function | RHA interacts with LARP6, which recruits RHA to the 5' UTR of collagen mRNAs. There, RHA activity is necessary for efficient formation of polysomes and a high level of collagen protein synthesis | Homo sapiens |