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Literature summary for 3.6.4.13 extracted from

  • Tang, W.; You, W.; Shi, F.; Qi, T.; Wang, L.; Djouder, Z.; Liu, W.; Zeng, X.
    RNA helicase A acts as a bridging factor linking nuclear beta-actin with RNA polymerase II (2009), Biochem. J., 420, 421-428.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
-
Homo sapiens
-
HeLa cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
RHA
-
Homo sapiens
RNA helicase A
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens polymerase II can interact with beta-actin, and this interaction is enhanced due to the overexpression of RNA helicase A up

General Information

General Information Comment Organism
malfunction knockdown of endogenous RHA significantly reduces the interaction of RNA polymerase II with beta-actin Homo sapiens
physiological function the enzyme plays an important role in linking beta-actin with RNA polymerase II and functions in gene transcription regulation Homo sapiens