Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Nonidet P-40 | - |
Gallus sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
geldanamycin | - |
Escherichia coli | |
geldanamycin | Hsp90 | Gallus sp. |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Gallus sp. | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mo6+ | - |
Gallus sp. | |
V5+ | - |
Gallus sp. |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
90000 | - |
2 * 90000, SDS-PAGE | Gallus sp. |
184000 | - |
native PAGE | Gallus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | Escherichia coli | - |
ADP + phosphate | - |
? | |
ATP + H2O | Neurospora crassa | - |
ADP + phosphate | - |
? | |
ATP + H2O | Gallus sp. | - |
ADP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Gallus sp. | - |
chicken | - |
Neurospora crassa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Neurospora crassa |
- |
Gallus sp. |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Escherichia coli | |
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Neurospora crassa | |
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Gallus sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | - |
Gallus sp. | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | - |
Escherichia coli | ADP + phosphate | - |
? | |
ATP + H2O | - |
Neurospora crassa | ADP + phosphate | - |
? | |
ATP + H2O | - |
Gallus sp. | ADP + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Escherichia coli |
dimer | 2 * 90000, SDS-PAGE | Gallus sp. |
oligomer | - |
Escherichia coli |
oligomer | critical temperature of 50°C defines transition from dimers to higher order oligomers | Gallus sp. |
Synonyms | Comment | Organism |
---|---|---|
Hsp90 molecular chaperone | - |
Neurospora crassa |
Hsp90 molecular chaperone | - |
Gallus sp. |