Cloned (Comment) | Organism |
---|---|
wild-type enzyme NPP1 and NPP1-DELTA804-905 is expressed in COS cells as fusions with enhanced green fluorescent protein | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
DELTA804-905 | mutation results in complete loss of activity, protein remains entirely intracellular | Mus musculus |
K173Q | polymorphisms of NPP1 is associated with the aetiology of insulin resistance, does not affect the dimerization or catalytic activity of NPP1 and does not endow NPP1 with an affinity for the insulin receptor | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Mus musculus | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P06802 | expressed as haemagglutinin-tagged fusion protein in COS-1 cells or HeLa cells | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
p-nitrophenyl thymidine 5'-monophosphate + H2O | - |
Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
nucleotide pyrophosphatase/phosphodiesterase NPP1 | - |
Mus musculus |