Data extracted from this reference:
Inhibitors
15-desoxybludein
0.065 mg/ml, 11% inhibition
Schistosoma mansoni
eremantolide C
0.065 mg/ml, 17% inhibition
Schistosoma mansoni
glaucolide A
0.065 mg/ml, 11% inhibition
Schistosoma mansoni
glaucolide B
0.065 mg/ml, 16% inhibition
Schistosoma mansoni
goyazensolide
0.065 mg/ml, 10% inhibition
Schistosoma mansoni
isogoyazensolide
0.065 mg/ml, 11% inhibition
Schistosoma mansoni
licnofolide
0.065 mg/ml, 22% inhibition
Schistosoma mansoni
additional information
no inhibition by 0.065 mg/ml 15-desoxygoyazensolide
Schistosoma mansoni
thapsigargicin
0.065 mg/ml, 57% inhibition
Schistosoma mansoni
thapsigargin
inhibits ATP hydrolysis, 70% inhibition at 0.065 mg/ml, mixed type inhibition, little or not affected by changes in free Ca2+ or Mg2+ concentrations, hydrolysis of ADP is not inhibited
Schistosoma mansoni
KM Value [mM]
0.0173
ATP
37°C, pH 7.4
Schistosoma mansoni
Organism
Substrates and Products (Substrate)
ATP + H2O
668024
Schistosoma mansoni
AMP + diphosphate
?
Synonyms
ATPDase
Schistosoma mansoni
ATPdiphosphohydrolase
Schistosoma mansoni
Ki Value [mM]
0.02
thapsigargin
37°C, pH 7.4, inhibition of ATP hydrolysis
Schistosoma mansoni
Inhibitors (protein specific)
15-desoxybludein
0.065 mg/ml, 11% inhibition
Schistosoma mansoni
eremantolide C
0.065 mg/ml, 17% inhibition
Schistosoma mansoni
glaucolide A
0.065 mg/ml, 11% inhibition
Schistosoma mansoni
glaucolide B
0.065 mg/ml, 16% inhibition
Schistosoma mansoni
goyazensolide
0.065 mg/ml, 10% inhibition
Schistosoma mansoni
isogoyazensolide
0.065 mg/ml, 11% inhibition
Schistosoma mansoni
licnofolide
0.065 mg/ml, 22% inhibition
Schistosoma mansoni
additional information
no inhibition by 0.065 mg/ml 15-desoxygoyazensolide
Schistosoma mansoni
thapsigargicin
0.065 mg/ml, 57% inhibition
Schistosoma mansoni
thapsigargin
inhibits ATP hydrolysis, 70% inhibition at 0.065 mg/ml, mixed type inhibition, little or not affected by changes in free Ca2+ or Mg2+ concentrations, hydrolysis of ADP is not inhibited
Schistosoma mansoni
Ki Value [mM] (protein specific)
0.02
thapsigargin
37°C, pH 7.4, inhibition of ATP hydrolysis
Schistosoma mansoni
KM Value [mM] (protein specific)
0.0173
ATP
37°C, pH 7.4
Schistosoma mansoni
Substrates and Products (Substrate) (protein specific)
ATP + H2O
668024
Schistosoma mansoni
AMP + diphosphate
?
Other publictions for EC 3.6.1.8
668024
Martins
Inhibition of the ecto-ATPdiph ...
Schistosoma mansoni
Biosci. Rep.
20
369-381
2000
-
-
-
-
-
-
10
1
-
-
-
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-
1
-
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-
-
-
-
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1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
10
1
1
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-
-
-
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-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
726055
Rashid
Characterization of a RecA/RAD ...
Thermococcus kodakarensis
Nucleic Acids Res.
25
719-726
1997
-
-
1
-
-
-
-
-
-
1
2
-
-
4
-
-
1
-
-
-
-
-
1
1
1
1
-
-
-
1
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-
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-
-
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-
1
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-
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-
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-
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-
1
2
-
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-
-
1
-
-
-
-
1
1
1
-
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-
1
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-
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-
210227
Masuda
A unique ectonucleotide pyroph ...
Sus scrofa
J. Clin. Invest.
95
699-704
1995
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-
-
-
-
-
-
2
2
-
2
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-
3
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-
1
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1
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1
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1
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2
2
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2
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1
-
1
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-
1
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-
-
1
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-
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-
210226
Capito
Presence of ATP-pyrophosphohyd ...
Mus musculus
Diabetes
35
1096-1100
1986
6
-
-
-
-
-
1
3
-
7
-
1
-
1
-
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-
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-
1
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1
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6
-
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-
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-
1
-
3
-
7
-
1
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-
1
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-
1
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-
-
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-
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-
-
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-
210225
Torp-Pedersen
Studies on a Ca2+-dependent nu ...
Rattus norvegicus
Biochim. Biophys. Acta
571
94-104
1979
-
-
-
-
-
-
2
2
1
4
1
2
-
2
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3
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4
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1
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2
1
2
1
4
1
2
-
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3
-
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4
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-
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-
210224
Flodgaard
A calcium ion-dependent adenos ...
Rattus norvegicus
Biochem. J.
171
817-820
1978
-
-
-
-
-
-
-
-
1
4
-
1
-
2
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-
1
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2
1
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3
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
4
-
1
-
-
-
1
-
2
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210223
Kawamura
Change in ATP-pyrophosphohydro ...
Physarum polycephalum
Biochim. Biophys. Acta
421
195-202
1976
-
-
-
-
-
-
2
-
-
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-
1
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2
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-
1
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1
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-
1
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-
2
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-
1
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-
1
-
1
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-
1
-
-
-
-
-
-
-
-
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-
-
-
-
-
-
210222
Kawamura
A calcium ion-dependent ATP py ...
Physarum polycephalum
Biochim. Biophys. Acta
397
207-219
1975
-
-
-
-
-
-
1
1
-
8
2
3
-
3
-
-
-
-
-
1
-
-
4
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
8
2
3
-
-
-
-
-
1
-
-
4
1
-
-
-
-
1
-
-
-
-
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-
-
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210221
Heppel
Mechanism of enzymatic hydroly ...
Bos taurus, Crotalus adamanteus, Oryctolagus cuniculus, Rattus norvegicus
J. Biol. Chem.
202
217-226
1953
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-
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4
-
5
-
4
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-
1
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-
2
-
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5
-
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-
1
-
1
2
-
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-
-
-
-
-
-
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4
-
5
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-
1
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2
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5
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1
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1
2
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