BRENDA - Reference to 3.6.1.8; Id = 668024

15-desoxybludein

0.065 mg/ml, 11% inhibition

Schistosoma mansoni

eremantolide C

0.065 mg/ml, 17% inhibition

Schistosoma mansoni

glaucolide A

0.065 mg/ml, 11% inhibition

Schistosoma mansoni

glaucolide B

0.065 mg/ml, 16% inhibition

Schistosoma mansoni

goyazensolide

0.065 mg/ml, 10% inhibition

Schistosoma mansoni

isogoyazensolide

0.065 mg/ml, 11% inhibition

Schistosoma mansoni

licnofolide

0.065 mg/ml, 22% inhibition

Schistosoma mansoni

additional information

no inhibition by 0.065 mg/ml 15-desoxygoyazensolide

Schistosoma mansoni

thapsigargicin

0.065 mg/ml, 57% inhibition

Schistosoma mansoni

thapsigargin

inhibits ATP hydrolysis, 70% inhibition at 0.065 mg/ml, mixed type inhibition, little or not affected by changes in free Ca2+ or Mg2+ concentrations, hydrolysis of ADP is not inhibited

Schistosoma mansoni

0.0173

-

ATP

37°C, pH 7.4

Schistosoma mansoni

-

ATP + H2O

-

668024

Schistosoma mansoni

AMP + diphosphate

-

?

0.02

-

thapsigargin

37°C, pH 7.4, inhibition of ATP hydrolysis

Schistosoma mansoni

15-desoxybludein

0.065 mg/ml, 11% inhibition

Schistosoma mansoni

eremantolide C

0.065 mg/ml, 17% inhibition

Schistosoma mansoni

glaucolide A

0.065 mg/ml, 11% inhibition

Schistosoma mansoni

glaucolide B

0.065 mg/ml, 16% inhibition

Schistosoma mansoni

goyazensolide

0.065 mg/ml, 10% inhibition

Schistosoma mansoni

isogoyazensolide

0.065 mg/ml, 11% inhibition

Schistosoma mansoni

licnofolide

0.065 mg/ml, 22% inhibition

Schistosoma mansoni

additional information

no inhibition by 0.065 mg/ml 15-desoxygoyazensolide

Schistosoma mansoni

thapsigargicin

0.065 mg/ml, 57% inhibition

Schistosoma mansoni

thapsigargin

inhibits ATP hydrolysis, 70% inhibition at 0.065 mg/ml, mixed type inhibition, little or not affected by changes in free Ca2+ or Mg2+ concentrations, hydrolysis of ADP is not inhibited

Schistosoma mansoni

0.02

-

thapsigargin

37°C, pH 7.4, inhibition of ATP hydrolysis

Schistosoma mansoni

0.0173

-

ATP

37°C, pH 7.4

Schistosoma mansoni

ATP + H2O

-

668024

Schistosoma mansoni

AMP + diphosphate

-

?

668024

Martins

Inhibition of the ecto-ATPdiph ...

Schistosoma mansoni

Biosci. Rep.

20

369-381

2000

-

10

1

-

1

-

1

-

1

-

10

1

-

1

-

726055

Rashid

Characterization of a RecA/RAD ...

Thermococcus kodakarensis

Nucleic Acids Res.

25

719-726

1997

-

1

-

1

2

-

4

-

1

-

1

-

1

-

1

-

1

2

-

1

-

1

-

1

-

210227

Masuda

A unique ectonucleotide pyroph ...

Sus scrofa

J. Clin. Invest.

95

699-704

1995

-

2

-

2

-

1

-

1

-

1

-

1

-

2

-

2

-

1

-

1

-

1

-

210226

Capito

Presence of ATP-pyrophosphohyd ...

Mus musculus

Diabetes

35

1096-1100

1986

6

-

1

3

-

7

-

1

-

1

-

1

-

1

-

6

-

1

-

3

-

7

-

1

-

1

-

1

-

210225

Torp-Pedersen

Studies on a Ca2+-dependent nu ...

Rattus norvegicus

Biochim. Biophys. Acta

571

94-104

1979

-

2

1

4

1

2

-

2

-

3

-

4

-

1

-

2

1

2

1

4

1

2

-

3

-

4

-

210224

Flodgaard

A calcium ion-dependent adenos ...

Rattus norvegicus

Biochem. J.

171

817-820

1978

-

1

4

-

1

-

2

-

1

-

2

1

-

3

-

1

4

-

1

-

1

-

2

1

-

3

-

210223

Kawamura

Change in ATP-pyrophosphohydro ...

Physarum polycephalum

Biochim. Biophys. Acta

421

195-202

1976

-

2

-

1

-

2

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

210222

Kawamura

A calcium ion-dependent ATP py ...

Physarum polycephalum

Biochim. Biophys. Acta

397

207-219

1975

-

1

-

8

2

3

-

3

-

1

-

4

1

-

1

-

1

-

1

-

8

2

3

-

1

-

4

1

-

1

-

210221

Heppel

Mechanism of enzymatic hydroly ...

Bos taurus, Crotalus adamanteus, Oryctolagus cuniculus, Rattus norvegicus

J. Biol. Chem.

202

217-226

1953

-

4

-

5

-

4

-

1

-

2

-

5

-

1

-

1

2

-

4

-

5

-

1

-

2

-

5

-

1

-

1

2

-

Inhibition of the ecto-ATPdiphosphohydrolase of Schistosoma mansoni by thapsigargin

Data extracted from this reference: