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Literature summary for 3.6.1.62 extracted from

  • Lykke-Andersen, J.
    Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay (2002), Mol. Cell. Biol., 22, 8114-8121.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
E148Q mutant enzyme is as stable as the wild-type enzyme Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm primarily localized in cytoplasm Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
m7G5'ppp5'-mRNA + H2O Homo sapiens
-
m7GDP + 5'-phospho-mRNA
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8IU60
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
m7G5'ppp5'-mRNA + H2O
-
Homo sapiens m7GDP + 5'-phospho-mRNA
-
?

Synonyms

Synonyms Comment Organism
hDcp2
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
assay at Homo sapiens