Literature summary for 3.6.1.60 extracted from

Grisanzio, C.; Werner, L.; Takeda, D.; Awoyemi, B.C.; Pomerantz, M.M.; Yamada, H.; Sooriakumaran, P.; Robinson, B.D.; Leung, R.; Schinzel, A.C.; Mills, I.; Ross-Adams, H.; Neal, D.E.; Kido, M.; Yamamoto, T.; Petrozziello, G.; Stack, E.C.; Lis, R.; Kantoff, P.W.; Loda, M.; Sartor, O.; Egawa, S.; Tewari, A.K.
Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis (2012), Proc. Natl. Acad. Sci. USA, 109, 11252-11257.

Application

Application	Comment	Organism
medicine	suppressing the expression of NUDT11, SLC22A3, and HNF1B influences cellular phenotypes associated with tumor-related properties in prostate cancer cells. 4 of the 12 known risk polymorphisms are strongly associated with transcripts NUDT11, MSMB, NCOA4, SLC22A3, and HNF1B in histologically normal tissue. Although associations are also observed in tumor tissue, they tend to be more attenuated	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	Q96G61	-	-

Synonyms	Comment	Organism
NUDT11	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)