Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.6.1.6 extracted from

  • Paganini, C.; Monti, L.; Costantini, R.; Besio, R.; Lecci, S.; Biggiogera, M.; Tian, K.; Schwartz, J.M.; Huber, C.; Cormier-Daire, V.; Gibson, B.G.; Pirog, K.A.; Forlino, A.; Rossi, A.
    Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification (2018), Matrix Biol., 81, 70-90 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.6

Protein Variants

Protein Variants Comment Organism
R302H inactive Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Mus musculus 5783
-
Golgi apparatus
-
 Mus musculus 5794
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ activates Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP + H2O Mus musculus
-
 UMP + phosphate + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q8VCF1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
chondrocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP + H2O
-
 Mus musculus UMP + phosphate + H+
-
 ?

Synonyms

Synonyms Comment Organism
calcium activated nucleotidase 1
-
 Mus musculus
Cant1
-
 Mus musculus

General Information

General Information Comment Organism
malfunction enzyme knock-out mice recapitulate the desbuquois dysplasia type 1 phenotype Mus musculus
physiological function the enzyme is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification Mus musculus