Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Escherichia coli |
Crystallization (Comment) | Organism |
---|---|
the crystal structures of MutT in the apo and holo forms and in the binary and ternary forms complexed with the product 8-oxo-dGMP and 8-oxo-dGMP plus Mn2+, respectively, are determined | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
8-oxo-dGTP + H2O | Escherichia coli | the activity of MutT can prevent the misincorporation of 8-oxoguanine opposite adenine in DNA | 8-oxo-dGMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P08337 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
8-oxo-dGTP + H2O | the activity of MutT can prevent the misincorporation of 8-oxoguanine opposite adenine in DNA | Escherichia coli | 8-oxo-dGMP + diphosphate | - |
? | |
8-oxo-dGTP + H2O | MutT exhibits high substrate specificity for 8-oxoguanine nucleotides by the ligand-induced conformational change | Escherichia coli | 8-oxo-dGMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MutT | - |
Escherichia coli |