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Literature summary for 3.6.1.52 extracted from

  • Hua, L.V.; Hidaka, K.; Pesesse, X.; Barnes, L.D.; Shears, S.B.
    Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases (2003), Biochem. J., 373, 81-89.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.52

Cloned(Commentary)

Cloned (Comment) Organism
expression in Epicurian coli Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
23000
-
 native enzyme, Western-blot analysis Mus musculus
25000
-
 recombinant enzyme, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
diphosphoinositol polyphosphate + H2O Mus musculus metabolism of diphosphoinositol polyphosphate, not hydrolysis of diadenosine polyphosphates inositol polyphosphate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P0C028
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
no modification
-
 Mus musculus

Purification (Commentary)

Purification (Comment) Organism
by nickel-agarose affinity chromatography Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-phospho-alpha-D-ribose 1-diphosphate + H2O not competes with diphosphoinositol pentakisphosphate Mus musculus 5-phospho-alpha-D-ribose 1-phosphate + phosphate
-
 ?
bisdiphosphoinositol tetrakisphosphate + H2O
-
 Mus musculus diphosphoinositol pentakisphosphate + phosphate
-
 ?
diphosphoinositol pentakisphosphate + H2O
-
 Mus musculus inositol hexakisphosphate + phosphate
-
 ?
diphosphoinositol polyphosphate + H2O metabolism of diphosphoinositol polyphosphate, not hydrolysis of diadenosine polyphosphates Mus musculus inositol polyphosphate + phosphate
-
 ?
diphosphoinositol polyphosphate + H2O preferred as substrate over diadenosine hexaphosphate Mus musculus inositol polyphosphate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
diphosphoinositol polyphosphate phosphohydrolase
-
 Mus musculus
DIPP3
-
 Mus musculus