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Literature summary for 3.6.1.5 extracted from

  • Tonin, A.; Da Silva, A.; Zanini, D.; Pelinson, L.; Schetinger, M.; Camillo, G.; Vogel, F.; de La Rue, M.; Jaques, J.; Lopes, S.
    Biochemical detection of enzymes NTPDase in tachyzoites of Toxoplasma gondii and possible functional correlations (2015), Comp. Clin. Pathol., 24, 393-397 .
No PubMed abstract available
Search for more literature for 3.6.1.5

Inhibitors

Inhibitors Comment Organism Structure
azide inhibition of NTPDase activity of the Toxoplasma gondii is directly proportional to the largest concentration of azide used to ATP and ADP substratum Toxoplasma gondii

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required Toxoplasma gondii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + H2O Toxoplasma gondii
-
 AMP + phosphate
-
 ?
ADP + H2O Toxoplasma gondii RH
-
 AMP + phosphate
-
 ?
ATP + H2O Toxoplasma gondii
-
 ADP + phosphate
-
 ?
ATP + H2O Toxoplasma gondii RH
-
 ADP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Toxoplasma gondii
-
 propagated in BALB/c mice
-
Toxoplasma gondii RH
-
 propagated in BALB/c mice
-

Source Tissue

Source Tissue Comment Organism Textmining
tachyzoite
-
 Toxoplasma gondii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + H2O
-
 Toxoplasma gondii AMP + phosphate
-
 ?
ADP + H2O
-
 Toxoplasma gondii RH AMP + phosphate
-
 ?
ATP + H2O
-
 Toxoplasma gondii ADP + phosphate
-
 ?
ATP + H2O
-
 Toxoplasma gondii RH ADP + phosphate
-
 ?
additional information the activity of NTPDase for substrate ATP is superior to ADP. For the hydrolysis of ATP, a decreasing curve is observed, since increased concentration of substrate consequently reduces NTPDase activity. The opposite occurs with the hydrolysis of ADP, since increases in NTPDase activity are directly proportional to the elevation of substrate in the reaction Toxoplasma gondii ?
-
-
additional information the activity of NTPDase for substrate ATP is superior to ADP. For the hydrolysis of ATP, a decreasing curve is observed, since increased concentration of substrate consequently reduces NTPDase activity. The opposite occurs with the hydrolysis of ADP, since increases in NTPDase activity are directly proportional to the elevation of substrate in the reaction Toxoplasma gondii RH ?
-
-

Synonyms

Synonyms Comment Organism
NTPDase
-
 Toxoplasma gondii

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
-
 Toxoplasma gondii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Toxoplasma gondii