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Literature summary for 3.6.1.43 extracted from

  • Rush, J.S.; Cho, S.K.; Jiang, S.; Hofmann, S.L.; Waechter, C.J.
    Identification and characterization of a cDNA encoding a dolichyl pyrophosphate phosphatase located in the endoplasmic reticulum of mammalian cells (2002), J. Biol. Chem., 277, 45226-45234.
    View publication on PubMed
Search for more literature for 3.6.1.43

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Saccharomyces cerevisiae, COS cells and Sf-9 insect cells Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Mus musculus 5783
-

Organism

Organism UniProt Comment Textmining
Mus musculus Q9JMF7 DLPP1 gene
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.005
-
 pH 7, 30°C, Dol-P-P phosphatase activity using microsomal fractions from Sf-9 cells expressing the enzyme Mus musculus
0.016
-
 pH 7, 30°C, Dol-P-P phosphatase activity using microsomal fractions from COS cells expressing the enzyme Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dolichyl diphosphate + H2O
-
 Mus musculus dolichyl phosphate + phosphate
-
 ?
additional information enzyme can not hydrolyse dolichyl monophospate Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
Dol-P-P phosphatase
-
 Mus musculus
dolichyl pyrophosphate phosphatase
-
 Mus musculus