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Literature summary for 3.6.1.28 extracted from
- Membrane-associated thiamin triphosphatase. II. Activation by divalent cations (1976), J. Biol. Chem., 251, 193-197.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | excess of Mg2+ over thiamine triphosphate inhibits | Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | associated | Rattus norvegicus | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | divalent cation requirement is satisfied by Mg2+, Mn2+ or Ca2+ | Rattus norvegicus | |
| Mg2+ | the true substrate may be the Mg2+-thiamine-triphosphate complex | Rattus norvegicus | |
| Mg2+ | divalent cation requirement is satisfied by Mg2+, Mn2+ or Ca2+ | Rattus norvegicus | |
| Mn2+ | divalent cation requirement is satisfied by Mg2+, Mn2+ or Ca2+ | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| thiamine triphosphate + H2O | - |
Rattus norvegicus | thiamine diphosphate + phosphate | - |
? | |
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Release 2023.1 (January 2023)
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