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Literature summary for 3.6.1.23 extracted from

  • Persson, R.; Harkiolaki, M.; McGeehan, J.; Wilson, K.S.
    Crystallization and preliminary crystallographic analysis of deoxyuridine 5'-triphosphate nucleotidohydrolase from Bacillus subtilis (2001), Acta Crystallogr. Sect. D, 57, 876-878.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
vapour diffusion method, cocrystallized with dUDP and Sr2+ Bacillus subtilis

Inhibitors

Inhibitors Comment Organism Structure
dUDP
-
Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dUTP + H2O Bacillus subtilis removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA dUMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dUTP + H2O
-
Bacillus subtilis dUMP + diphosphate
-
?
dUTP + H2O removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA Bacillus subtilis dUMP + diphosphate
-
?