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Literature summary for 3.6.1.17 extracted from

  • Robinson, A.K.; de la Pena C.E.; Barnes, L.D.
    Isolation and charcterization of diadenosine tetraphosphate (Ap4A) hydrolase from Schizosaccharomyces pombe (1993), Biochim. Biophys. Acta, 1161, 139-148.
    View publication on PubMed
Search for more literature for 3.6.1.17

Activating Compound

Activating Compound Comment Organism Structure
beta-mercaptoethanol slight activation Saccharomyces cerevisiae
dithiothreitol slight activation Saccharomyces cerevisiae
phosphate activating below 30 mM Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
fluoride no effect Saccharomyces cerevisiae
phosphate inhibitory above 30 mM Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
22000
-
 SDS-PAGE Saccharomyces cerevisiae
49000
-
 gel filtration Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O Saccharomyces cerevisiae
-
 ATP + AMP
-
 ?
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O Saccharomyces cerevisiae
-
 GTP + GMP
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 Schizosaccharomyces pombe
-

Purification (Commentary)

Purification (Comment) Organism
partial Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
 Saccharomyces cerevisiae ATP + AMP
-
 ?
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
 Saccharomyces cerevisiae GTP + GMP
-
 ?