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Literature summary for 3.6.1.17 extracted from

  • Cameselle, J.C.; Costas, M.J.; Sillero, M.A.G.; Sillero, A.
    Two low Km hydrolytic activities on dinucleoside 5',5'''-P1,P4-tetraphosphates in rat liver. Characterization as the specific dinucleoside tetraphosphatase and a phosphodiesterase-I-like enzyme (1984), J. Biol. Chem., 259, 2879-2885.
    View publication on PubMed
Search for more literature for 3.6.1.17

Inhibitors

Inhibitors Comment Organism Structure
Ca2+
-
 Rattus norvegicus
guanosine 5'-tetraphosphate Ki in nanomolar range Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.001
-
 P1,P4-bis(5'-guanosyl) tetraphosphate
-
 Rattus norvegicus
0.005
-
 P1,P4-bis(5'-adenosyl) tetraphosphate
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
22000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
 Rattus norvegicus ATP + AMP
-
 ?
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
 Rattus norvegicus GTP + GMP
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Rattus norvegicus