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Literature summary for 3.6.1.17 extracted from

  • Moreno, A.; Lobaton, C.D.; Sillero, M.A.G.; Sillero, A.
    Dinucleosidetetraphosphatase from Ehrlich ascites tumour cells: inhibition by adenosine, guanosine and uridine 5-tetraphosphates (1982), Int. J. Biochem., 14, 629-634.
    View publication on PubMed
Search for more literature for 3.6.1.17

Inhibitors

Inhibitors Comment Organism Structure
adenosine 5'-tetraphosphate Ki in nanomolar range Mus musculus
ADP
-
 Mus musculus
AMP
-
 Mus musculus
ATP
-
 Mus musculus
GDP
-
 Mus musculus
GMP
-
 Mus musculus
GTP
-
 Mus musculus
guanosine 5'-tetraphosphate Ki in nanomolar range Mus musculus
UDP
-
 Mus musculus
uridine 5'-tetraphosphate Ki in nanomolar range Mus musculus
UTP
-
 Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required, maximum activity at 1 mM Mus musculus
Mn2+ required, maximum activity at 0.5 mM Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
19800
-
 gel filtration Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O Mus musculus
-
 ATP + AMP
-
 ?
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O Mus musculus
-
 GTP + GMP
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
Ehrlich ascites carcinoma cell
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0074
-
 crude exctract Mus musculus
0.276
-
 partially purified enzyme Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
 Mus musculus ATP + AMP
-
 ?
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
 Mus musculus GTP + GMP
-
 ?
P1,P4-bis(5'-xanthosyl) tetraphosphate + H2O
-
 Mus musculus XTP + XMP
-
 ?