Cloned (Comment) | Organism |
---|---|
nsp13, expression of the His-tagged enzyme in insect cells | Human coronavirus 229E |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | the enzyme contains an N-terminal zinc binding domain | Human coronavirus 229E |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human coronavirus 229E | - |
HCoV-229E | - |
Purification (Comment) | Organism |
---|---|
recombinant His-tagged enzyme from insect cells | Human coronavirus 229E |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | - |
Human coronavirus 229E | ADP + phosphate | - |
? | |
dATP + H2O | - |
Human coronavirus 229E | dADP + phosphate | - |
? | |
GTP + H2O | - |
Human coronavirus 229E | GDP + phosphate | - |
? | |
additional information | the enzyme hydrolyzes all natural ribonucleotides and nucleotides, the enzyme also mediates RNA 5'-triphosphatase activity using the NTPase active site, this activity is inhibited by ATP, overview | Human coronavirus 229E | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | the enzyme contains an N-terminal zinc binding domain and a C-terminal superfamily 1 helicase domain | Human coronavirus 229E |
Synonyms | Comment | Organism |
---|---|---|
nonstructural protein 13 | - |
Human coronavirus 229E |
nsp13 | - |
Human coronavirus 229E |
NTPase | - |
Human coronavirus 229E |