Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | potent noncompetitive inhibitor | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.169 | - |
ADPribose | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34000 | - |
2 * 34000, SDS-PAGE with and without mercaptoethanol | Homo sapiens |
68000 | - |
gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADPribose + H2O | Homo sapiens | the enzyme may play an important role in the regulation of intracellular steady-state of free ADPribose | AMP + D-ribose 5-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
8.59 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-20°C, no loss of activity after months | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP-glucose + H2O | at 21% of the activity with ADPribose | Homo sapiens | AMP + alpha-D-glucose 1-phosphate | - |
? | |
ADP-mannose + H2O | at 70% of the activity with ADPribose | Homo sapiens | AMP + D-mannose 1-phosphate | - |
? | |
ADPribose + H2O | - |
Homo sapiens | AMP + D-ribose 5-phosphate | - |
? | |
ADPribose + H2O | the enzyme may play an important role in the regulation of intracellular steady-state of free ADPribose | Homo sapiens | AMP + D-ribose 5-phosphate | - |
? | |
CDP-glucose + H2O | at 5% of the activity with ADPribose | Homo sapiens | CMP + glucose 5-phosphate | - |
? | |
GDP-mannose + H2O | at 40% of the activity with ADPribose | Homo sapiens | GMP + D-mannose 1-phosphate | - |
? | |
IDP-ribose + H2O | at 59% of the activity with ADPribose | Homo sapiens | IMP + ribose 5-phosphate | - |
? | |
UDP-glucose + H2O | at 5% of the activity with ADPribose | Homo sapiens | UMP + glucose 5-phosphate | - |
? | |
UDP-mannose + H2O | at 20% of the activity with ADPribose | Homo sapiens | UMP + D-mannose 1-phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 34000, SDS-PAGE with and without mercaptoethanol | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9.5 | - |
- |
Homo sapiens |