Activating Compound | Comment | Organism | Structure |
---|---|---|---|
carbonyl cyanide-4-trifluoromethoxyphenylhydrazone | - |
Rhipicephalus microplus | |
dithiothreitol | about 50% stimulation of activity at 1 mM | Rhipicephalus microplus | |
pyruvate | - |
Rhipicephalus microplus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
heparin | the activity is completely inhibited by 0.02 mg/ml heparin | Rhipicephalus microplus | |
hydrogen peroxide | - |
Rhipicephalus microplus | |
potassium cyanide | - |
Rhipicephalus microplus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0002 | - |
Triphosphate | in 50 mM Tris-HCl buffer (pH 7.2), at 28°C | Rhipicephalus microplus | |
0.0022 | - |
sodium phosphate glass type 15 | in 50 mM Tris-HCl buffer (pH 7.2), at 28°C | Rhipicephalus microplus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial membrane | - |
Rhipicephalus microplus | 31966 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rhipicephalus microplus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | - |
Rhipicephalus microplus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sodium phosphate glass type 15 + H2O | - |
Rhipicephalus microplus | ? + phosphate | - |
? | |
triphosphate + H2O | - |
Rhipicephalus microplus | diphosphate + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
polyphosphate phosphohydrolase | - |
Rhipicephalus microplus |
PPX | - |
Rhipicephalus microplus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
1 | - |
in 50 mM Tris-HCl buffer (pH 7.2), at 28°C | Rhipicephalus microplus | hydrogen peroxide |
General Information | Comment | Organism |
---|---|---|
physiological function | exopolyphosphatase activity is regulated during mitochondrial respiration and plays a role in adenosine-5-triphosphate synthesis in hard tick embryos | Rhipicephalus microplus |