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Literature summary for 3.6.1.10 extracted from

  • Andreeva, N.; Trilisenko, L.; Eldarov, M.; Kulakovskaya, T.
    Polyphosphatase PPN1 of Saccharomyces cerevisiae: switching of exopolyphosphatase and endopolyphosphatase activities (2015), PLoS ONE, 10, e0119594.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.10

Activating Compound

Activating Compound Comment Organism Structure
ADP ATP inhibits while ADP activates endopolyphosphatase activity in the presence of Mg2+ Saccharomyces cerevisiae

Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
ATP ATP inhibits while ADP activates endopolyphosphatase activity in the presence of Mg2+ Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ in the presence of Mg2+, the enzyme shows a polyphosphate chain fragmentation activity Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae Q04119 bifunctional exo- and endopolyphosphatase, EC 3.6.1.11 and EC 3.6.1.10
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Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification PPN1 gene encodes a polypeptide with the predicted molecular mass of 78 kDa, the monomer molecular mass of the mature PPN1 is about 33-35 kDa Saccharomyces cerevisiae

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme is a bifunctional exo- and endopolyphosphatase, activities of ECs 3.6.1.11 and 3.6.1.10, respectively. No activity with diphosphate, ATP and 4-nitrophenyl phosphate Saccharomyces cerevisiae ?
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