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Literature summary for 3.5.99.7 extracted from

  • Nascimento, F.; Rossi, M.; Soares, C.; McConkey, B.; Glick, B.
    New insights into 1-aminocyclopropane-1-carboxylate (ACC) deaminase phylogeny, evolution and ecological significance (2014), PLoS ONE, 9, e99168.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.99.7

Protein Variants

Protein Variants Comment Organism
E295S/L322T the mutations lead to a loss of enzyme activity against 1-aminocyclopropane-1-carboxylate Pseudomonas putida

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.25
-
 D-Cystine pH and temperature not specified in the publication Arabidopsis thaliana
0.34
-
 D-Cystine mutant enzyme E295S/L322T, pH and temperature not specified in the publication Pseudomonas putida
0.8
-
 1-aminocyclopropane-1-carboxylate pH and temperature not specified in the publication Methylobacterium nodulans
1.1
-
 beta,beta-difluoro-D-alanine pH and temperature not specified in the publication Pseudomonas sp.
1.8
-
 1-aminocyclopropane-1-carboxylate pH and temperature not specified in the publication Methylobacterium radiotolerans
2.6
-
 1-aminocyclopropane-1-carboxylate pH and temperature not specified in the publication Cyberlindnera saturnus
3.4
-
 1-aminocyclopropane-1-carboxylate wild type enzyme, pH and temperature not specified in the publication Pseudomonas putida
4.4
-
 1-amino-2-vinylcyclopropane-1-carboxylic acid pH and temperature not specified in the publication Pseudomonas sp.
4.8
-
 1-aminocyclopropane-1-carboxylate pH and temperature not specified in the publication Penicillium citrinum
5.4
-
 beta-Chloro-D-alanine pH and temperature not specified in the publication Pseudomonas sp.
36.2
-
 DL-coronamic acid pH and temperature not specified in the publication Pseudomonas sp.
56
-
 O-acetyl-D-serine pH and temperature not specified in the publication Pseudomonas sp.
97
-
 D-vinylglycine pH and temperature not specified in the publication Pseudomonas sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-aminocyclopropane-1-carboxylate + H2O Arabidopsis thaliana
-
 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O Pseudomonas sp.
-
 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O Penicillium citrinum
-
 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O Cyberlindnera saturnus
-
 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O Methylobacterium radiotolerans
-
 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O Pseudomonas putida
-
 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O Bradyrhizobium japonicum
-
 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O Methylobacterium nodulans
-
 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O Bradyrhizobium japonicum USDA 110
-
 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O Pseudomonas putida UW4
-
 2-oxobutanoate + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Bradyrhizobium japonicum Q89XR6
-
-
Bradyrhizobium japonicum USDA 110 Q89XR6
-
-
Cyberlindnera saturnus
-
-
-
Methylobacterium nodulans
-
-
-
Methylobacterium radiotolerans
-
-
-
Penicillium citrinum
-
-
-
Pseudomonas putida Q5PWZ8
-
-
Pseudomonas putida UW4 Q5PWZ8
-
-
Pseudomonas sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-amino-2-vinylcyclopropane-1-carboxylic acid + H2O
-
 Pseudomonas sp. ?
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Arabidopsis thaliana 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Pseudomonas sp. 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Penicillium citrinum 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Cyberlindnera saturnus 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Methylobacterium radiotolerans 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Pseudomonas putida 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Bradyrhizobium japonicum 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Methylobacterium nodulans 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Bradyrhizobium japonicum USDA 110 2-oxobutanoate + NH3
-
 ?
1-aminocyclopropane-1-carboxylate + H2O
-
 Pseudomonas putida UW4 2-oxobutanoate + NH3
-
 ?
beta,beta-dichloro-D-alanine + H2O
-
 Pseudomonas sp. ?
-
 ?
beta,beta-difluoro-D-alanine + H2O
-
 Pseudomonas sp. ?
-
 ?
beta-chloro-D-alanine + H2O
-
 Pseudomonas sp. ?
-
 ?
beta-fluoro-D-alanine + H2O
-
 Pseudomonas sp. ?
-
 ?
D-cystine + H2O
-
 Arabidopsis thaliana ?
-
 ?
D-cystine + H2O
-
 Cyberlindnera saturnus ?
-
 ?
D-cystine + H2O
-
 Methylobacterium radiotolerans ?
-
 ?
D-cystine + H2O
-
 Pseudomonas putida ?
-
 ?
D-cystine + H2O
-
 Methylobacterium nodulans ?
-
 ?
D-cystine + H2O
-
 Pseudomonas putida UW4 ?
-
 ?
D-erythro-2-amino-3-chlorobutyrate + H2O
-
 Pseudomonas sp. ?
-
 ?
D-serine + H2O
-
 Pseudomonas sp. ?
-
 ?
D-serine + H2O
-
 Penicillium citrinum ?
-
 ?
D-serine + H2O
-
 Cyberlindnera saturnus ?
-
 ?
D-serine + H2O
-
 Bradyrhizobium japonicum ?
-
 ?
D-serine + H2O
-
 Bradyrhizobium japonicum USDA 110 ?
-
 ?
D-threo-2-amino-3-fluorobutyrate + H2O
-
 Pseudomonas sp. ?
-
 ?
D-vinylglycine + H2O
-
 Pseudomonas sp. ?
-
 ?
DL-coronamic acid + H2O
-
 Pseudomonas sp. ?
-
 ?
DL-coronamic acid + H2O
-
 Penicillium citrinum ?
-
 ?
DL-coronamic acid + H2O
-
 Cyberlindnera saturnus ?
-
 ?
L-cystine + H2O
-
 Methylobacterium radiotolerans ?
-
 ?
L-cystine + H2O
-
 Methylobacterium nodulans ?
-
 ?
L-serine + H2O
-
 Penicillium citrinum ?
-
 ?
additional information 1-aminocyclopentane-1-carboxylate, L-homoserine, L-Thr, L-Tryp, L-Met, L-Tyr, L-Cys, and L-aminobutyrate are not a functional substrate Pseudomonas sp. ?
-
 ?
additional information beta-chloro-D-alanine and O-acetyl-D-serine are not a functional substrate Cyberlindnera saturnus ?
-
 ?
additional information beta-chloro-D-alanine is not a functional substrate Bradyrhizobium japonicum ?
-
 ?
additional information DL-allocoronamic acid and dimethyl-1-aminocyclopropane-1-carboxylic acid are not a functional substrate Penicillium citrinum ?
-
 ?
additional information beta-chloro-D-alanine is not a functional substrate Bradyrhizobium japonicum USDA 110 ?
-
 ?
O-acetyl-D-serine + H2O
-
 Pseudomonas sp. ?
-
 ?

Synonyms

Synonyms Comment Organism
ACC deaminase
-
 Arabidopsis thaliana
ACC deaminase
-
 Pseudomonas sp.
ACC deaminase
-
 Penicillium citrinum
ACC deaminase
-
 Cyberlindnera saturnus
ACC deaminase
-
 Methylobacterium radiotolerans
ACC deaminase
-
 Pseudomonas putida
ACC deaminase
-
 Bradyrhizobium japonicum
ACC deaminase
-
 Methylobacterium nodulans
AcdS
-
 Arabidopsis thaliana
AcdS
-
 Pseudomonas sp.
AcdS
-
 Penicillium citrinum
AcdS
-
 Cyberlindnera saturnus
AcdS
-
 Methylobacterium radiotolerans
AcdS
-
 Pseudomonas putida
AcdS
-
 Bradyrhizobium japonicum
AcdS
-
 Methylobacterium nodulans