Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-deoxy-2-amino-D-glucitol 6-phosphate | - |
Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.4 | - |
D-glucosamine 6-phosphate | pH 7.8, 25°C | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
alpha-D-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3 | reaction mechanism involves a ring-opening step, followed by an enolization step that proceeds through a cis-enolamine and its tautomeric imine as reaction intermediates | Escherichia coli |
Storage Stability | Organism |
---|---|
0-5°C, in liquid N2, little loss of activity after 2-5 months | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucosamine 6-phosphate + H2O | active towards alpha-anomer, inactive towards the beta-anomer. Strong affinity for the open-chain form of glucosamine 6-phosphate | Escherichia coli | D-fructose 6-phosphate + NH3 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 28000-30000, SDS-PAGE | Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
2-deoxy-2-amino-D-glucitol 6-phosphate | pH 7.8, 25°C, substrate : D-glucosamine-6-phosphate | Escherichia coli |