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Literature summary for 3.5.5.1 extracted from

  • Kamila, S.; Zhu, D.; Biehl, E.R.; Hua, L.
    Unexpected stereorecognition in nitrilase-catalyzed hydrolysis of beta-hydroxy nitriles (2006), Org. Lett., 8, 4429-4431.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Bradyrhizobium japonicum
-
USDA110
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Bradyrhizobium japonicum USDA 110
-
USDA110
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-(2,4-dichlorophenyl)-3-hydroxypropanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum (S)-3-(2,4-dichlorophenyl)-3-hydroxypropanoic acid + NH3
-
?
3-(2,4-dichlorophenyl)-3-hydroxypropanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum USDA 110 (S)-3-(2,4-dichlorophenyl)-3-hydroxypropanoic acid + NH3
-
?
3-(2-chlorophenyl)-3-hydroxypropanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum 3-(2-chlorophenyl)-3-hydroxypropanoic acid + NH3
-
?
3-(2-chlorophenyl)-3-hydroxypropanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum USDA 110 3-(2-chlorophenyl)-3-hydroxypropanoic acid + NH3
-
?
3-(4-chlorophenyl)-3-hydroxypropanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum (S)-3-(4-chlorophenyl)-3-hydroxypropanoic acid + NH3
-
?
3-(4-chlorophenyl)-3-hydroxypropanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum USDA 110 (S)-3-(4-chlorophenyl)-3-hydroxypropanoic acid + NH3
-
?
3-(4-fluorophenyl)-3-hydroxypropanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum (S)-3-(4-fluorophenyl)-3-hydroxypropanoic acid + NH3
-
?
3-(4-fluorophenyl)-3-hydroxypropanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum USDA 110 (S)-3-(4-fluorophenyl)-3-hydroxypropanoic acid + NH3
-
?
3-hydroxy-3-(2-methoxyphenyl)propanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum (S)-3-hydroxy-3-(2-methoxyphenyl)propanoic acid + NH3
-
?
3-hydroxy-3-(2-methoxyphenyl)propanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum USDA 110 (S)-3-hydroxy-3-(2-methoxyphenyl)propanoic acid + NH3
-
?
3-hydroxy-3-(3-methoxyphenyl)propanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum (S)-3-hydroxy-3-(3-methoxyphenyl)propanoic acid + NH3
-
?
3-hydroxy-3-(4-methoxyphenyl)propanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum (S)-3-hydroxy-3-(4-methoxyphenyl)propanoic acid + NH3
-
?
3-hydroxy-3-(4-methylphenyl)propanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum (S)-3-hydroxy-3-(4-methylphenyl)propanoic acid + NH3
-
?
3-hydroxy-3-phenylpropanenitrile + H2O nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles Bradyrhizobium japonicum (S)-3-hydroxy-3-phenylpropanoic acid + NH3
-
?
hydroxy(phenyl)acetonitrile + H2O hydrolysis of alpha-hydroxynitriles is not enantioselective Bradyrhizobium japonicum ?
-
?

Synonyms

Synonyms Comment Organism
nitrilase bll6402
-
Bradyrhizobium japonicum