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Literature summary for 3.5.4.9 extracted from

  • Tremblay, G.B.; Mejia, N.R.; MacKenzie, R.E.
    The NADP-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase is not expressed in Spodoptera frugiperda cells (1992), J. Biol. Chem., 267, 8281-8285.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Rattus norvegicus 5737
-
cytoplasm
-
Saccharomyces cerevisiae 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5,10-methenyltetrahydrofolate + H2O Rattus norvegicus
-
10-formyltetrahydrofolate
-
?
5,10-methenyltetrahydrofolate + H2O Saccharomyces cerevisiae
-
10-formyltetrahydrofolate
-
?
5,10-methenyltetrahydrofolate + H2O Spodoptera frugiperda
-
10-formyltetrahydrofolate
-
?
5,10-methenyltetrahydrofolate + H2O Spodoptera frugiperda Sf9
-
10-formyltetrahydrofolate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
rat, trifunctional cytoplasmic enzyme
-
Saccharomyces cerevisiae
-
yeast, trifunctional enzyme
-
Spodoptera frugiperda
-
-
-
Spodoptera frugiperda Sf9
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methenyltetrahydrofolate + H2O
-
Rattus norvegicus 10-formyltetrahydrofolate
-
?
5,10-methenyltetrahydrofolate + H2O
-
Saccharomyces cerevisiae 10-formyltetrahydrofolate
-
?
5,10-methenyltetrahydrofolate + H2O
-
Spodoptera frugiperda 10-formyltetrahydrofolate
-
?
5,10-methenyltetrahydrofolate + H2O
-
Spodoptera frugiperda Sf9 10-formyltetrahydrofolate
-
?

Synonyms

Synonyms Comment Organism
bifunctional methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
-
Spodoptera frugiperda