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Literature summary for 3.5.4.5 extracted from

  • Matsubara, T.; Dupuis, M.; Aida, M.
    The ONIOM molecular dynamics method for biochemical applications: cytidine deaminase (2007), Chem. Phys. Lett., 437, 138-142.
No PubMed abstract available
Search for more literature for 3.5.4.5

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cytidine + H2O Homo sapiens
-
 uridine + NH3
-
 ?
additional information Homo sapiens cytidine deaminase plays an important role in the activation of the anticancer drug capesitabine in the human body ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cytidine + H2O
-
 Homo sapiens uridine + NH3
-
 ?
cytidine + H2O development and implementation of the ONIOM-molecular dynamics method with cytidine deaminase as model enzyme for determination of activity and biochemical properties, product uridine is strongly perturbed by the thermal motion of the environment and dissociates easily from the active site, overview Homo sapiens uridine + NH3
-
 ?
additional information cytidine deaminase plays an important role in the activation of the anticancer drug capesitabine in the human body Homo sapiens ?
-
 ?