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Literature summary for 3.5.4.4 extracted from

  • Da Silva, A.S.; Baldissera, M.D.; Bottari, N.B.; Gabriel, M.E.; Rhoden, L.A.; Piva, M.M.; Christ, R.; Stedille, F.A.; Gris, A.; Morsch, V.M.; Schetinger, M.R.; Mendes, R.E.
    Oxidative stress and changes in adenosine deaminase activity of cattle experimentally infected by Fasciola hepatica (2017), Parasitology, 144, 520-526 .
    View publication on PubMed
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Organism

Organism UniProt Comment Textmining
Bos taurus P56658 Friesian male cattle
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Source Tissue

Source Tissue Comment Organism Textmining
blood serum from Friesian male cattle. Animals infected with Fasciola hepatica show lower enzyme activity on days 40 and 60 post infection compared with the uninfected control. The reduction on seric activity on days 40 and 60 post-inection can contribute to restrict the inflammatory response, and the subsequent cellular damage Bos taurus
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liver from Friesian male cattle. Activity increases on day 100 post-infection (with Fasciola hepatica) contributed to the intense inflammatory process and oxidative damage due to the depletion of adenosine levels, an antiinflammatory molecule Bos taurus
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Synonyms

Synonyms Comment Organism
ADA
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 Bos taurus

General Information

General Information Comment Organism
metabolism important enzyme in the purine metabolism. Oxidative stress occurs in cattle experimentally infected by Fasciola hepatica, mainly due to excessive production of reactive oxygen species in the course of fasciolosis, contributing to hepatic damage. Increase in hepatic adenosine deaminase activity may contribute to the inflammatory process Bos taurus