Protein Variants | Comment | Organism |
---|---|---|
D172 | mutant is 40% less active than the wild-type. Mutant is more thightly bound to erythro-9-(2-hydroxy-3-nonly)adenine (Ki: 0.0009 mM) than wild-type | Plasmodium vivax |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | - |
Plasmodium vivax |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.071 | - |
adenosine | wild-type, pH 7.5, 37°C | Plasmodium vivax |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium vivax | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenosine + H2O | - |
Plasmodium vivax | inosine + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PvADA | - |
Plasmodium vivax |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Plasmodium vivax |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Plasmodium vivax |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0009 | - |
(2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | mutant D172A, pH 7.5, 30°C | Plasmodium vivax | |
0.0019 | - |
(2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | wild-type, pH 7.5, 30°C | Plasmodium vivax |