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Literature summary for 3.5.4.38 extracted from

  • Ito, F.; Fu, Y.; Kao, S.A.; Yang, H.; Chen, X.S.
    Family-wide comparative analysis of cytidine and methylcytidine deamination by eleven human APOBEC proteins (2017), J. Mol. Biol., 429, 1787-1799 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.4.38

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P31941
-
-
Homo sapiens Q6NTF7
-
-
Homo sapiens Q8IUX4
-
-
Homo sapiens Q96AK3
-
-
Homo sapiens Q9HC16
-
-
Homo sapiens Q9NRW3
-
-
Homo sapiens Q9UH17
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cytosine in single-stranded DNA + H2O deamination activity of methylated cytosine is demonstrated APOBEC3B Homo sapiens uracil in single-stranded DNA + NH3
-
 ?
cytosine in single-stranded DNA + H2O high deaminase activities on cytosine and methylated cytosine with relatively high selectivity for methylated cytosine Homo sapiens uracil in single-stranded DNA + NH3
-
 ?
cytosine in single-stranded DNA + H2O relatively low deaminase activity and selectivity for methylated cytosine Homo sapiens uracil in single-stranded DNA + NH3
-
 ?

Synonyms

Synonyms Comment Organism
APOBEC3A
-
 Homo sapiens
APOBEC3B
-
 Homo sapiens
APOBEC3C
-
 Homo sapiens
APOBEC3D
-
 Homo sapiens
APOBEC3F
-
 Homo sapiens
APOBEC3G
-
 Homo sapiens
APOBEC3H
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
-
 Homo sapiens
6.5
-
-
 Homo sapiens