Protein Variants | Comment | Organism |
---|---|---|
E56A | mutation in subunit Tad2, mutant enzyme has no deaminase activity in vitro | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenine34 in tRNA + H2O | Saccharomyces cerevisiae | - |
hypoxanthine34 in tRNA + NH3 | - |
? | |
adenine34 in tRNA + H2O | Saccharomyces cerevisiae ATCC 204508 | - |
hypoxanthine34 in tRNA + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P47058 and Q9URQ3 | P47058: TAD2 and Q9URQ3: TAD3 | - |
Saccharomyces cerevisiae ATCC 204508 | P47058 and Q9URQ3 | P47058: TAD2 and Q9URQ3: TAD3 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenine34 in tRNA + H2O | - |
Saccharomyces cerevisiae | hypoxanthine34 in tRNA + NH3 | - |
? | |
adenine34 in tRNA + H2O | - |
Saccharomyces cerevisiae ATCC 204508 | hypoxanthine34 in tRNA + NH3 | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | the heterodimeric enzyme consists of two sequence-related subunits (Tad2p/ADAT2 and Tad3p/ADAT3), both of which contain cytidine deaminase motifs | Saccharomyces cerevisiae |