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Literature summary for 3.5.4.33 extracted from

  • Rubio, M.A.; Pastar, I.; Gaston, K.W.; Ragone, F.L.; Janzen, C.J.; Cross, G.A.; Papavasiliou, F.N.; Alfonzo, J.D.
    An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA (2007), Proc. Natl. Acad. Sci. USA, 104, 7821-7826.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
adenine34 in tRNAThr(AGU) + H2O Trypanosoma brucei
-
 hypoxanthine34 in tRNAThr(IGU) + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenine34 in tRNAThr(AGU) + H2O
-
 Trypanosoma brucei hypoxanthine34 in tRNAThr(IGU) + NH3
-
 ?
adenine34 in tRNAThr(AGU) + H2O in vitro, this enzyme can mediate A-to-I editing of tRNA and C-to-U deamination of ssDNA Trypanosoma brucei hypoxanthine34 in tRNAThr(IGU) + NH3
-
 ?

Synonyms

Synonyms Comment Organism
adenosine-to-inosine tRNA-editing enzyme
-
 Trypanosoma brucei