Cloned (Comment) | Organism |
---|---|
- |
Aquifex aeolicus |
Crystallization (Comment) | Organism |
---|---|
hanging drop vapor diffusion method, 1.8 A resolution. The large cavity formed around the catalytic site with the zinc ion seems to be important for accommodating the anticodon loop stem of tRNAArg-2 | Aquifex aeolicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | TadA contains endogenous Zn2+ ions. Zn2+ is tetrahedrally coordinated by His52, Cys82, Cys85, and a water | Aquifex aeolicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenine34 in tRNAArg2 + H2O | Aquifex aeolicus | the bacterial tRNA adenosine deaminase generates inosine by deaminating the adenosine residue at the wobble position of tRNAArg-2. This modification is essential for the decoding system | hypoxanthine34 in tRNAArg2 + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aquifex aeolicus | O67050 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Aquifex aeolicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenine34 in tRNAArg2 + H2O | - |
Aquifex aeolicus | hypoxanthine34 in tRNAArg2 + NH3 | - |
? | |
adenine34 in tRNAArg2 + H2O | the bacterial tRNA adenosine deaminase generates inosine by deaminating the adenosine residue at the wobble position of tRNAArg-2. This modification is essential for the decoding system | Aquifex aeolicus | hypoxanthine34 in tRNAArg2 + NH3 | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Aquifex aeolicus |
Synonyms | Comment | Organism |
---|---|---|
TadA | - |
Aquifex aeolicus |