KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.011 | - |
guanine | - |
Sus sp. | |
0.33 | - |
8-Azaguanine | - |
Sus sp. |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
2 * 50000, SDS-PAGE | Mus musculus |
50000 | - |
2 * 50000, SDS-PAGE | Oryctolagus cuniculus |
50000 | - |
2 * 50000, SDS-PAGE | Sus sp. |
55000 | - |
- |
Rattus norvegicus |
55000 | - |
- |
Oryctolagus cuniculus |
110000 | - |
- |
Rattus norvegicus |
110000 | - |
- |
Oryctolagus cuniculus |
110000 | - |
brain, gel filtration | Sus sp. |
170000 | - |
- |
Oryctolagus cuniculus |
207000 | - |
- |
Oryctolagus cuniculus |
525000 | - |
- |
Oryctolagus cuniculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
guanine + H2O | Mus musculus | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Rattus norvegicus | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Oryctolagus cuniculus | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Platyrrhini | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Ovis ammon | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Sus sp. | - |
xanthine + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
mouse | - |
Oryctolagus cuniculus | - |
rabbit | - |
Ovis ammon | - |
sheep | - |
Platyrrhini | - |
- |
- |
Rattus norvegicus | - |
rat | - |
Sus sp. | - |
pig | - |
Purification (Comment) | Organism |
---|---|
- |
Sus sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
brain | - |
Rattus norvegicus | - |
brain | - |
Oryctolagus cuniculus | - |
brain | - |
Sus sp. | - |
liver | - |
Mus musculus | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Oryctolagus cuniculus | - |
Storage Stability | Organism |
---|---|
4°C, 0.1 M phosphate buffer, 2 mM 2-mercaptoethanol, pH 7.5, stable for at least 3 months | Sus sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-thioguanine + H2O | - |
Oryctolagus cuniculus | 6-thioxanthine + NH3 | - |
? | |
6-thioguanine + H2O | - |
Sus sp. | 6-thioxanthine + NH3 | - |
? | |
8-azaguanine + H2O | - |
Sus sp. | 8-azaxanthine + NH3 | - |
? | |
guanine + H2O | - |
Mus musculus | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Rattus norvegicus | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Oryctolagus cuniculus | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Platyrrhini | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Ovis ammon | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Sus sp. | xanthine + NH3 | - |
? | |
additional information | high specificity towards guanine, 2-amino-6-chloropurine, 8-bromoguanine, 7-methylguanine, thioguanine, guanosine, guanosine 5'-monophosphate, guanilic acid, adenosine and 2-aminopurine are no substrates | Sus sp. | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Rattus norvegicus |
dimer | 2 * 50000, SDS-PAGE | Mus musculus |
dimer | 2 * 50000, SDS-PAGE | Oryctolagus cuniculus |
dimer | 2 * 50000, SDS-PAGE | Sus sp. |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.5 | 10 | - |
Sus sp. |