Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dAMP | at low substrate, dCMP, concentration: activation at higher concentration of either: inhibition | Equus asinus | |
dCTP | allosteric activator | Equus asinus | |
dCTP | allosteric activator, increases substrate affinity | Equus asinus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dAMP | at low substrate, dCMP, concentration: activation at higher concentration of either: competitive inhibition; competitive inhibitor, activates enzyme at low substrate concentration mimicing the cooperative effect of the substrate | Equus asinus | |
dTTP | allosteric inhibitor | Equus asinus | |
dUMP | competitive inhibition, kinetics and mechanism of inhibition | Equus asinus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetic studies, steady-state kinetics, allosteric kinetics | Equus asinus | |
0.024 | - |
dCMP | in the presence of dCTP | Equus asinus | |
0.037 | - |
dCMP | in the presence of dCTP | Equus asinus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
120000 | - |
- |
Equus asinus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dCMP + H2O | Equus asinus | - |
dUMP + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Equus asinus | - |
donkey | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
dCMP + H2O = dUMP + NH3 | mechanism | Equus asinus | |
dCMP + H2O = dUMP + NH3 | regulation, allosteric end-product regulation | Equus asinus | |
dCMP + H2O = dUMP + NH3 | highly regulated allosteric enzyme | Equus asinus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
spleen | - |
Equus asinus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dCMP + H2O | - |
Equus asinus | dUMP + NH3 | - |
? |
Subunits | Comment | Organism |
---|---|---|
hexamer | 6 identical subunits | Equus asinus |