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Literature summary for 3.5.4.10 extracted from
- On the purification and mechanism of action of 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase from chicken liver (1981), Biochemistry, 20, 337-344.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| IMP | minor 5% IMP contaminant in the substrate found to have no effects on the inosinicase assay | Gallus gallus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide | Gallus gallus | de novo purine synthesis step 10 | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 154-fold | Gallus gallus |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 5.09 | - |
at 25°C | Gallus gallus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide | de novo purine synthesis step 10 | Gallus gallus | ? | - |
? | |
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