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Literature summary for 3.5.4.1 extracted from
- Cytosine deaminase producing Clostridium may be used in detection of tumors (2006), Med. Hypotheses, 67, 1257-1258.
Application
| Application | Comment | Organism |
|---|---|---|
| diagnostics | the enzyme, expressed by Clostridium sp., can be used for detection of Clostridia-containing tumors in humans using clostridial directed 5-fluorouracil prodrug therapy | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Clostridium sp. | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-fluorocytosine + H2O | recombinant enzyme expressed in Clostridium sp. | Homo sapiens | 5-fluorouracil + NH3 | - |
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Release 2023.1 (January 2023)
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