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Literature summary for 3.5.3.6 extracted from

  • Kim, J.E.; Kim, S.Y.; Lee, K.W.; Lee, H.J.
    Arginine deiminase originating from Lactococcus lactis ssp. lactis American Type Culture Collection (ATCC) 7962 induces G1-phase cell-cycle arrest and apoptosis in SNU-1 stomach adenocarcinoma cells (2009), Br. J. Nutr., 102, 1469-1476.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Lactococcus lactis subsp. lactis

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Lactococcus lactis subsp. lactis 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arginine + H2O Lactococcus lactis subsp. lactis
-
 L-citrulline + NH3
-
 ?
L-arginine + H2O Lactococcus lactis subsp. lactis ATCC 7962
-
 L-citrulline + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Lactococcus lactis subsp. lactis Q2HYA0
-
-
Lactococcus lactis subsp. lactis ATCC 7962 Q2HYA0
-
-

Purification (Commentary)

Purification (Comment) Organism
Q-Sepharose column chromatography and Sephacryl-S200 gel filtration Lactococcus lactis subsp. lactis

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O
-
 Lactococcus lactis subsp. lactis L-citrulline + NH3
-
 ?
L-arginine + H2O
-
 Lactococcus lactis subsp. lactis ATCC 7962 L-citrulline + NH3
-
 ?

Synonyms

Synonyms Comment Organism
ADI
-
 Lactococcus lactis subsp. lactis

General Information

General Information Comment Organism
physiological function ADI induces apoptosis and G0/G1-phase arrest of SNU-1cells, which may contribute to the chemopreventive potential of lactic acid bacteria Lactococcus lactis subsp. lactis