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Literature summary for 3.5.3.18 extracted from

  • Wang, D.; Gill, P.S.; Chabrashvili, T.; Onozato, M.L.; Raggio, J.; Mendonca, M.; Dennehy, K.; Li, M.; Modlinger, P.; Leiper, J.; Vallance, P.; Adler, O.; Leone, A.; Tojo, A.; Welch, W.J.; Wilcox, C.S.
    Isoform-specific regulation by N(G),N(G)-dimethylarginine dimethylaminohydrolase of rat serum asymmetric dimethylarginine and vascular endothelium-derived relaxing factor/NO (2007), Circ. Res., 101, 627-635.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q6MG60
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Source Tissue

Source Tissue Comment Organism Textmining
blood vessel DDAH-2 is strongly expressed in blood vessels Rattus norvegicus
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liver expression of mRNA for DDAH-1 is 7fold higher in the liver compared to DDAH-2 Rattus norvegicus
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renal cortex expression of mRNA for DDAH-1 is 2fold higher in the renal cortex compared to DDAH-2 Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NG,NG-dimethyl-L-arginine + H2O
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Rattus norvegicus dimethylamine + L-citrulline
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?

Synonyms

Synonyms Comment Organism
DDAH-2 isozyme Rattus norvegicus
dimethylarginine dimethylaminohydrolase
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Rattus norvegicus