Literature summary for 3.5.3.15 extracted from

Makrygiannakis, D.; Hermansson, M.; Ulfgren, A.K.; Nicholas, A.P.; Zendman, A.J.; Eklund, A.; Grunewald, J.; Skold, C.M.; Klareskog, L.; Catrina, A.I.
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells (2008), Ann. Rheum. Dis., 67, 1488-1492.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
bronchial mucosa	-	Homo sapiens	-
bronchoalveolar lavage	-	Homo sapiens	-
lung	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
protein L-Arg + H2O	-	Homo sapiens	protein citrulline + NH3	-	?

Synonyms

Synonyms	Comment	Organism
PAD2	-	Homo sapiens
peptidylarginine deiminase 2	-	Homo sapiens

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Release 2023.1 (January 2023)