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Literature summary for 3.5.3.15 extracted from

  • Chang, X.; Yamada, R.; Suzuki, A.; Sawada, T.; Yoshino, S.; Tokuhiro, S.; Yamamoto, K.
    Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis (2005), Rheumatology, 44, 40-50.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
fibrin L-arginine + H2O Homo sapiens citrullinated fibrin is a potential antigen of rheumatoid arthritis fibrin L-citrulline + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
 Homo sapiens
-
macrophage
-
 Homo sapiens
-
monocyte
-
 Homo sapiens
-
neutrophil
-
 Homo sapiens
-
PBMC
-
 Homo sapiens
-
synovial tissue high abundance of PADI14 in the synovial membrane is a prominent feature of rheumatoid arthritis Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fibrin L-arginine + H2O
-
 Homo sapiens fibrin L-citrulline + NH3
-
 ?
fibrin L-arginine + H2O citrullinated fibrin is a potential antigen of rheumatoid arthritis Homo sapiens fibrin L-citrulline + NH3
-
 ?

Synonyms

Synonyms Comment Organism
PADI4
-
 Homo sapiens
peptidylarginine deiminase 4
-
 Homo sapiens