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Literature summary for 3.5.3.1 extracted from

  • Xie, X.; Wang, C.; Wang, Z.
    Microcalorimetric studies on the non-competitive inhibition of bovine liver arginase (2004), J. Therm. Anal. Calorim., 77, 1005-1012.
No PubMed abstract available
Search for more literature for 3.5.3.1

Inhibitors

Inhibitors Comment Organism Structure
Sodium fluoride noncompetitive Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.98
-
 L-arginine pH 9.4, 37°C, presence of 0.1 mM Mn2+ Bos taurus
5.14
-
 L-arginine pH 9.4, 37°C Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ exogenous addition of Mn2+ results in increased sensitivity to inhibitor sodium fluoride Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O
-
 Bos taurus L-ornithine + urea
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.38
-
 Sodium fluoride pH 7.4, 37°C, thermokinetic method, presence of 0.167 mM Mn2+ Bos taurus
0.51
-
 Sodium fluoride pH 7.4, 37°C, thermokinetic method Bos taurus
1.48
-
 Sodium fluoride pH 7.4, 37°C, initial rate method, presence of 0.167 mM Mn2+ Bos taurus
1.84
-
 Sodium fluoride pH 7.4, 37°C, initial rate method Bos taurus