Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.2.6 extracted from

  • Hiraiwa, Y.; Morinaka, A.; Fukushima, T.; Kudo, T.
    Metallo-beta-lactamase inhibitory activity of phthalic acid derivatives (2009), Bioorg. Med. Chem. Lett., 19, 5162-5165.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
3'-hydroxybiphenyl-2,3-dicarboxylic acid
-
Pseudomonas aeruginosa
3-(3-hydroxypropyl)benzene-1,2-dicarboxylic acid
-
Pseudomonas aeruginosa
3-methylbenzene-1,2-dicarboxylic acid
-
Pseudomonas aeruginosa
4'-hydroxybiphenyl-2,3-dicarboxylic acid
-
Pseudomonas aeruginosa
4-butyl-3-methylbenzene-1,2-dicarboxylic acid
-
Pseudomonas aeruginosa
4-butylbenzene-1,2-dicarboxylic acid
-
Pseudomonas aeruginosa
biphenyl-2,2',3-tricarboxylic acid
-
Pseudomonas aeruginosa
biphenyl-2,3,3'-tricarboxylic acid
-
Pseudomonas aeruginosa
biphenyl-2,3,4'-tricarboxylic acid
-
Pseudomonas aeruginosa
biphenyl-2,3-dicarboxylic acid
-
Pseudomonas aeruginosa
trisodium 2'-oxidobiphenyl-2,3-dicarboxylate
-
Pseudomonas aeruginosa

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
MSC15369, IMP-1 is PCR amplified from plasmid DNA prepared from a carbapenems-resistant Pseudomonas aeruginosa MSC15369. The PCR product is cloned into pTrcHis2 TOPO vector (Invitrogen, Carlsbad, CA) and expressed in Escherichia coli DH5a after induction with 0.5 mM isopropyl-beta-D-(-)-thiogalactopyranoside for 3 h at room temperature
-

Purification (Commentary)

Purification (Comment) Organism
-
Pseudomonas aeruginosa

Synonyms

Synonyms Comment Organism
IMP-1
-
Pseudomonas aeruginosa

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000968
-
pH and temperature not specified in the publication Pseudomonas aeruginosa biphenyl-2,3-dicarboxylic acid
0.00155
-
pH and temperature not specified in the publication Pseudomonas aeruginosa 4'-hydroxybiphenyl-2,3-dicarboxylic acid
0.00175
-
pH and temperature not specified in the publication Pseudomonas aeruginosa 3'-hydroxybiphenyl-2,3-dicarboxylic acid
0.00225
-
pH and temperature not specified in the publication Pseudomonas aeruginosa biphenyl-2,3,4'-tricarboxylic acid
0.00244
-
pH and temperature not specified in the publication Pseudomonas aeruginosa trisodium 2'-oxidobiphenyl-2,3-dicarboxylate
0.013
-
pH and temperature not specified in the publication Pseudomonas aeruginosa 3-(3-hydroxypropyl)benzene-1,2-dicarboxylic acid
0.016
-
pH and temperature not specified in the publication Pseudomonas aeruginosa 4-butyl-3-methylbenzene-1,2-dicarboxylic acid
0.0179
-
pH and temperature not specified in the publication Pseudomonas aeruginosa biphenyl-2,3,3'-tricarboxylic acid
0.16
-
pH and temperature not specified in the publication Pseudomonas aeruginosa 3-methylbenzene-1,2-dicarboxylic acid
0.207
-
pH and temperature not specified in the publication Pseudomonas aeruginosa biphenyl-2,2',3-tricarboxylic acid
0.243
-
pH and temperature not specified in the publication Pseudomonas aeruginosa 4-butylbenzene-1,2-dicarboxylic acid