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Literature summary for 3.5.2.2 extracted from
- C-terminal regions of D-hydantoinases are nonessential for catalysis, but affect the oligomeric structure (1998), Biochem. Biophys. Res. Commun., 243, 96-100.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | - |
Geobacillus stearothermophilus |
| synthesis | - |
Geobacillus thermocatenulatus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cDNA sequences of dihydropyrimidinase determined | Homo sapiens |
| cDNA sequences of dihydropyrimidinase determined | Rattus norvegicus |
| gene cloned and sequenced, identical with B. stearothermophilus NS1122A gene | Geobacillus thermocatenulatus |
| strain SD1, D-hydantoinase gene cloned and sequenced | Geobacillus stearothermophilus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hydantoin + H2O | Homo sapiens | - |
N-carbamoyl glycine | - |
? |  |
| hydantoin + H2O | Rattus norvegicus | - |
N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | Geobacillus stearothermophilus | - |
N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | Pseudomonas putida | - |
N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | Geobacillus thermocatenulatus | - |
N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | Geobacillus stearothermophilus SD-1 | - |
N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | Geobacillus thermocatenulatus GH-2 | - |
N-carbamoyl glycine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Geobacillus stearothermophilus | - |
- |
- |
| Geobacillus stearothermophilus | - |
strains NS1122A and LU1220 | - |
| Geobacillus stearothermophilus SD-1 | - |
- |
- |
| Geobacillus thermocatenulatus | - |
- |
- |
| Geobacillus thermocatenulatus GH-2 | - |
- |
- |
| Homo sapiens | - |
human | - |
| Pseudomonas putida | - |
DSM 84, formerly classified as P. fluorescens | - |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Geobacillus stearothermophilus |
- |
Geobacillus thermocatenulatus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 5 | - |
mutant BS460 | Geobacillus stearothermophilus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hydantoin + H2O | - |
Geobacillus stearothermophilus | hydantoic acid | - |
? | |
| hydantoin + H2O | - |
Geobacillus thermocatenulatus | hydantoic acid | - |
? | |
| hydantoin + H2O | - |
Geobacillus stearothermophilus SD-1 | hydantoic acid | - |
? | |
| hydantoin + H2O | - |
Geobacillus thermocatenulatus GH-2 | hydantoic acid | - |
? | |
| hydantoin + H2O | - |
Homo sapiens | N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | - |
Rattus norvegicus | N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | - |
Geobacillus stearothermophilus | N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | - |
Pseudomonas putida | N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | - |
Geobacillus thermocatenulatus | N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | - |
Geobacillus stearothermophilus SD-1 | N-carbamoyl glycine | - |
? | |
| hydantoin + H2O | - |
Geobacillus thermocatenulatus GH-2 | N-carbamoyl glycine | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | - |
Geobacillus stearothermophilus |
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