Literature summary for 3.5.1.98 extracted from

Feng, J.H.; Jing, F.B.; Fang, H.; Gu, L.C.; Xu, W.F.
Expression, purification, and S-nitrosylation of recombinant histone deacetylase 8 in Escherichia coli (2011), Biosci. Trends, 5, 17-22.

Search for more literature for 3.5.1.98

Cloned(Commentary)

Cloned (Comment)	Organism
isoform HDAC8, expression in Escherichia coli	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
S-nitrosocysteine	the activity of HDAC8 is significantly inhibited when incubated with S-nitrosoglutathione and S-nitrosocysteine in a time- and dosage-dependent manner. Sodium nitroprusside and dithiothreitol cannot reverse this inhibition	Homo sapiens
S-nitrosoglutathione	HDAC8 can be S-nitrosylated by S-nitrosoglutathione in vitro, and the activity of HDAC8 is significantly inhibited when incubated with S-nitrosoglutathione and S-nitrosocysteine in a time- and dosage-dependent manner. Sodium nitroprusside and dithiothreitol cannot reverse this inhibition	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
42000	-	x * 42000, SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9BY41	histone deacetylase 8	-

Subunits

Subunits	Comment	Organism
?	x * 42000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
HD8	-	Homo sapiens

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Release 2023.1 (January 2023)